Oleocanthal chemical structure
Bioactive intrinsic compound of high phenolic extra virgin olive oil
Extra Virgin olive oil (EVOO) is credited as being one of the many healthful components associated with the Cretan diet under the Mediteranian nutrition. EVOO is rich in phenolic compounds as Oleocanthal and the health promoting benefits of these phenolics are now established.
The health claim for polyphenols in olive oil Regarding olive oil, 16 petitions belonging to the category Article 13.1 (a) ‘general function’ claims of the regulation were submitted. The only authorised health claim, listed in the Commission Regulation (EU) No 432/2012, relates to the level of olive phenolic compounds and the impact on the protection of blood lipids from oxidative stress.
Furthermore EVOO polyphenols: chemical composition and characteristics The EFSA Panel considered that polyphenols can be characterised by their content of hydroxytyrosol and its derivatives (e.g. oleocanthal and oleuropein complex).
[Bach-Faig, A.;Berry, E.M.; Lairon, D.; Reguant, J.; Trichopoulou, A.; Dernini, S.; Medina, F.X.; Battino, M.; Belahsen, R.; Miranda, G. Mediterranean diet pyramid today. Science and cultural updates. Public Health Nutri. 2011, 14, 2274–2284; Sahyoun, N.R.; Sankavaram, K. Historical origins of the Mediterranean Diet, Regional Dietary Profiles, and the Development of the Dietary Guidelines. In Mediterranean Diet; Springer: Cham, Switzerland, 2016; pp. 43–56]
Tripoli, E.; Giammanco, M.; Tabacchi, G.; Di Majo, D.; Giammanco, S.; La Guardia, M. The phenolic compounds of olive oil: Structure, biological activity and beneficial effects on human health. Nutr. Res. Rev. 2005, 18, 98–112]; Serra-Majem, L.; Trichopoulou, A. Trichopoulou, Updating the Benefits of the Mediterranean Diet: From the Heart to the Earth. In Mediterranean Diet; Springer: Cham, Switzerland, 2016; pp. 3–14].
[Caramia, G.; Gori, A.; Valli, E.; Cerretani, L. Virgin olive oil in preventive medicine: From legend to epigenetics. Eur. J. Lipid Sci. Technol. 2012, 114, 375– 388].in preventive medicine: From legend to epigenetics. Eur. J. Lipid Sci. Technol. 2012, 114, 375– 388].
[Covas, M.-I.; Fitó, M.; de la Torre, R. Minor Bioactive Olive Oil Components and Health: Key Data for Their Role in Providing Health Benefits in Humans. In Olive and Olive Oil Bioactive Constituents; Elsevier, Inc.: Philadelphia, PA, USA, 2015; p. 31.].
[Estruch, R.; Ros, E.; Salas-Salvadó, J.; Covas, M.-I.; Corella, D.; Arós, F.; Gómez-Gracia, E.; Ruiz-Gutiérrez, V.; Fiol, M.; Lapetra, J.; et al. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N. Engl. J. Med. 2013, 368, 1279–1290].
[Cicerale, S.; Lucas, L.; Keast, R. Antimicrobial, antioxidant and anti-inflammatory phenolic activities in extra virgin olive oil. Curr. Opin. Biotechnol. 2012, 23, 129–135].
Efficacy of Early Harvest Olive Oil in Cognition of Primary (PPMS) or Secondary (SPMS) Progressive Multiple Sclerosis
The Effect of Extra Virgin Olive Oil in People With Multiple Sclerosis
ECNE Research Article
The Health Benefiting Mechanisms of Virgin Olive Oil Phenolic Compounds
Projects - World Olive Center for Health
Elaias Karpos Article
Iraklio News Article